She joined the Greek Diplomatic Service in 1984 and since 2016 is the Head of the Directorate of International Environmental Conferences and Climate Change at the Ministry of Foreign Affairs.

She previously served as Ambassador to Norway and  Iceland as well as Chief of Protocol and Director for Cultural Affairs in the Foreign Ministry. Before that she served in several positions in the Embassies of Greece in Brussels, Prague and Pretoria, and the Consulates General in New York and Geneva. Earlier in her career she dealt with Turkey, Cyprus and USA bilateral relations and was the Head of the Greek Delegations to CSCE and UNCTAD during Greek Presidencies of the European Union.

Ambassador  Loupas has been a member of the Governing Bodies of the European Cultural Centre in Delphi, the Hellenic Culture Centre and the Hellenic Institute of Byzantine and post-Byzantine Studies in Venice, as well as  an honorary member of several Associations and Committees in New York, Geneva and Oslo. She has a notable and longstanding track record in the organization of successful international events in the political, social, economic and cultural fields.